The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...

The offensive line of the San Francisco 49ers hasn't been too shabby this season. But that doesn't mean they can't use some ...

The Buffalo Bills are fresh off of their bye week heading into a Sunday Night Football matchup with the San Francisco 49ers, ...

Being without Brock Purdy against the Green Bay Packers stung the San Francisco 49ers. It essentially chalked up the game as ...

But a week after allowing the Bears to dominate them on third down (9 of 16) and fourth down (3 of 3), failing to generate a ...

The 49ers just lost 38-10 to the Green Bay Packers. Here are the 49ers' grades for this performance. QUARTERBACK: C-MINUS.

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...

The San Francisco 49ers face a tough challenge on Sunday, traveling to Wisconsin to take on the Green Bay Packers.

Two words can sum up the Week 12 matchup between the visiting San Francisco 49ers and the host Green Bay Packers: utter ...

After the Green Bay Packers moved to 8-3, things are looking rosy as far as playoff qualification goes. Here's what to know.

The banged-up 49ers suffered a blowout loss to the Packers on Sunday, and their playoff outlook is becoming more bleak.

Green Bay's first-year defensive coordinator bristled at reporters' questions ahead of Sunday's showdown with San Francisco.