With the Lions' offense practically unstoppable and their defense taking a big hit at linebacker, a high-scoring shootout is expected against the Colts at Lucas Oil Stadium.

There are too many scenarios in which Stafford is going to top this number – a dominant home win, a back-and-forth slugfest, or a crushing defeat. At home, against the hot Philadelphia Eagles, most rankings have Cooper Kupp and Puka Nacua in the top seven or eight fantasy receivers. The same guy is throwing to both of them – win, lose or tie.