Medications at the time of presentation included lisinopril 10 mg p.o. once daily, warfarin sodium 2 mg p.o. once daily, furosemide 40 mg p.o. once daily, potassium chloride 20 meq p.o. once daily ...

Low event rates and short TTRs with warfarin were notable, and questions persist as to which patients truly need OAC.

Patients who receive a heart valve replacement are well-known to be at a high risk for stroke, blood clots and deep vein ...

Edoxaban, a medication taken orally to prevent blood clots from forming, was found to be as effective and safe for stroke and ...

Edoxaban, an oral anticoagulant, was equally or more effective than warfarin in reducing the risk of stroke and blood clots for patients after heart valve replacement surgery, according to preliminary ...

Patients stable on warfarin therapy and concurrently taking a cyclooxygenase-2 (COX-2) inhibitor comparator ... randomly received celecoxib 200 mg/day or rofecoxib 25 mg/day for three weeks.

Patients who received edoxaban did experience higher instances of gastrointestinal bleeding compared to patients who received warfarin (2.1% vs ... either edoxaban (60 mg or 30 mg taken orally ...

The FDA informed Intercept that it is unable to approve the sNDA in its current form, consistent with the outcome of the Gastrointestinal Drugs Advisory Committee (GIDAC) meeting in September 2024. In ...