Pre-surgery treatment with the novel drug vidutolimod and the PD-1 checkpoint inhibitor nivolumab led to tumor control in 55% of patients with stage 3 cutaneous melanoma, according to the results ...

Oral tolerance is an important feature of gut immune homeostasis but how it is maintained is not fully known. Here authors show in a mouse model that dietary nucleic acids activate the MAVS and ...

Modern immunology is based on experimental observations that may be 'translated' to the clinic to prevent and treat diseases. In China, modern immunological research dates back to the 1930s. At ...

Studies in humans and mice show that myocardial infarction recruits monocytes to the brain’s thalamus, promoting sleep, which in turn restricts cardiac inflammation and sympathetic signalling ...

In the final episode, experts at UCSD and La Jolla Institute discuss current clinical trials of a cancer vaccine and future directions for neoantigen vaccines. Custom-made Cancer Therapy ...

Oct. 31, 2024 — A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through which aging may ...