In the quest to enhance the efficacy of chimeric antigen receptor T (CAR-T) cell therapy against hepatocellular carcinoma (HCC), a recent study has identified a pivotal role for CD39 expression in ...

Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...

Additionally, the CAR-M produced pro-inflammatory cytokines and adopted an inflammatory ... Inhibition of Tumor Infiltrating Myeloid derived Suppressor cells, Promotion of Tumor Infiltrating T-cells, ...

However, this reaction can backfire in someone who has excessive body fat, and the fat storage cells are overly full. As fat storage cells get larger, this attracts invasion by immune cells that ...

Results The detection of cytokines characteristic for T cells and myeloid cells in the expected ... the key cytokine driving bone destruction by osteoclast activation, is produced by synovial B cells ...

Operator Good afternoon, and welcome to AbCellera's Q3 2024 business update conference call. My name is Tamia, and I will ...

Amtagvi Infusions: A total of 146 patients have been infused with Amtagvi since the first commercial infusion in April 2024, including 25 patients infused in the second quarter, 82 patients infused in ...

By improving the balance of bacteria in the gut, probiotics might inhibit pro-inflammatory factors and signaling pathways and ...

Researchers say study offers proof-of-concept that targeting how T cells interact with metabolites in their environment can ...

TCRclub integrates scRNA-seq and scTCR-seq data by local harmony to identify functionally similar T cell groups, termed ...

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T ...