In short, these results revealed that both CRLF2 OE and CRLF2-d are correlated with poor prognosis in ALL patients.

Sickness-induced sleep is a behavior conserved across species that promotes recovery from illness, yet the underlying mechanisms are poorly understood. Here, we show that interleukin-6-like cytokine ...

GlobalData’s report assesses the drugs in the Interleukin 10 Receptor pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

Inflammation and genetic mutations can drive cardiovascular complications in patients with myeloproliferative neoplasms, which include disorders such as polycythemia vera, essential thrombocythemia, ...

Each cytokine acts through its own receptor on target cells, and these receptors include members of the immunoglobulin (Ig) superfamily and tumour necrosis factor (TNF). Immunocytokines are ...

It is not inevitable that H5N1 will develop into a pandemic -- if we act now. Unfortunately, instead of urgent action, we ...

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats.

Find out all you need to know about bispecific antibodies, including how they work and what the current clinical landscape ...

The fall flurry of biotech IPOs shows no signs of abating, with Upstream Bio becoming the latest company to express an ...

Scientists at the Medical College of Georgia at Augusta University are searching for a new treatment target for a common ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...