In short, these results revealed that both CRLF2 OE and CRLF2-d are correlated with poor prognosis in ALL patients.

Sickness-induced sleep is a behavior conserved across species that promotes recovery from illness, yet the underlying mechanisms are poorly understood. Here, we show that interleukin-6-like cytokine ...

It is not inevitable that H5N1 will develop into a pandemic -- if we act now. Unfortunately, instead of urgent action, we ...

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats.

Find out all you need to know about bispecific antibodies, including how they work and what the current clinical landscape ...

The fall flurry of biotech IPOs shows no signs of abating, with Upstream Bio becoming the latest company to express an ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

This mtDNA can activate Toll-like receptor 9 (TLR9), triggering the nuclear factor kappa-B (NF-κB) signaling pathway and leading to the production of inflammatory cytokines. These cytokines ...

Zhijian “James” Chen received this year’s Albert Lasker Award for discovering cGAS, an enzyme which scopes out DNA-based ...

By fighting off pathogens, the specialized cells of our immune systems help to keep us healthy and free of infectious diseases. Immunotherapies teach those same cells to recognize and destroy cancer.