IL2RB (CD122), IL4R (CD124), IL7R (CD127), IL9R (CD129) and IL21R, along with IL2RG, are all members of the γc family of cytokine receptors. The γc subunit forms distinct heterodimeric receptors ...

In short, these results revealed that both CRLF2 OE and CRLF2-d are correlated with poor prognosis in ALL patients.

GlobalData’s report assesses the drugs in the Interleukin 10 Receptor pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

By fighting off pathogens, the specialized cells of our immune systems help to keep us healthy and free of infectious diseases. Immunotherapies teach those same cells to recognize and destroy cancer.

Sickness-induced sleep is a behavior conserved across species that promotes recovery from illness, yet the underlying mechanisms are poorly understood. Here, we show that interleukin-6-like cytokine ...

The CCL17/CCL22-CCR4 axis can be used as a novel biomarker for the prognosis of B-cell acute lymphoblastic leukemia (ALL), according to a new study published in the journal Cytokine. It is already ...

The leading Toll-Like Receptor 4 (TLR-4) Agonist Companies such as Eisai, Akaza Bioscience, OPNT-003, GeNeuro, MN-166 ...

Bile acids are byproducts of cholesterol metabolism in the liver and constitute the primary components of bile. Disruption of ...

Legend Biotech's valuation is conservative, suggesting potential for significant appreciation and growth ahead. Click here to ...

Adaptimmune received FDA approval for Tecelra, with a 39% response rate in synovial sarcoma. See why I rate ADAP stock as a ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

B-cells, crucial components of the adaptive immune system, play a multifaceted role in immune defense through antibody production, cytokine release, and antigen presentation to T-cells. By producing ...