Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

The San Francisco 49ers expect to get quarterback Brock Purdy back for their Week 13 matchup with the Buffalo Bills. That’s ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

There are no teams on bye around the NFL in Week 13, which means we'll be treated to a packed slate of Sunday games even ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

Preview the Week 13 matchup between the Buffalo Bills and San Francisco 49ers with predictions, odds, over/under, spread, ...

San Francisco 49ers quarterback Brock Purdy is expected to return to the field on Sunday against the Buffalo Bills after ...

Purdy missed the 49ers' Week 12 contest versus the Green Bay Packers last Sunday with a right shoulder injury—a game San ...

A light dusting of snow began covering the Buffalo Bills' facility on Friday as the team completed its final practice of the ...

If the 49ers can't break out of their funk, here are three maneuvers they should consider down the home stretch.

Buffalo Bills coach Sean McDermott ruled out Dalton Kincaid from playing against San Francisco on Sunday night, while holding ...

Brock Purdy is expected to return Sunday night against the Bills, but offensive tackle Trent Williams, defensive end Nick ...