Researchers at the ESMO Congress presented data showing better responses on dual-checkpoint blockade in the biomarker-defined ...
The French firm has a lead metastatic colorectal cancer vaccine candidate headed for Phase I/IIA trials, in which it will explore ways of predicting response.
The firms will collaborate on two lead programs and up to five future targets in other diseases, with NanoVation eligible for up to $600 million in payments from Novo Nordisk.
Analysis of ctDNA in the MARIPOSA trial showed fewer EGFR alterations and MET amplifications after Rybrevant-Lazcluze treatment than after Tagrisso.
Researchers analyzed molecular and particulate matter exposure data on nearly 9,000 NSCLC patients in France and confirmed a link reported by UK scientists in 2022.
The drug is approved in combination with an aromatase inhibitor as adjuvant therapy for breast cancer patients at high risk of recurrence.
Patients on therapies recommended by an MTB had better progression-free survival and overall response rates than those on standard-of-care therapy.
The firms will share data from the HERTHENA-Lung02 trial, in which patritumab deruxtecan improved patients' progression-free survival versus chemo.
The company said the single-arm multicenter Phase II trial may support accelerated approval for the RP-A501 gene therapy in the US.
Phase I data presented at ESMO suggested that TORL-1-23 may have particularly strong activity in CLDN-positive advanced ...
Experts noted, however, there is insufficient evidence to determine which commercially available KRAS G12C inhibitor is the ...
The adaptive basket trial, which matches patients to treatments based on complex biomarker signatures, could help shape ...