Tisch, 43, the Harvard-educated scion of a wealthy New York family, has worked for the city for 16 years, holding leadership roles in several agencies. As sanitation commissioner, she became TikTok famous when she declared in 2022, “The rats don’t run the city, we do.”

Sanitation boss Jessica Tisch was named Wednesday as the NYPD’s next commissioner — and sources tell The Post they expect her to clean house. Tisch, a longtime public servant and 12-year civilian NYPD veteran, will start in her new job Monday, Mayor Eric Adams announced from City Hall.