San Francisco 49ers head coach Kyle Shanahan reveals different preparations against the Los Angeles Rams without Aaron Donald ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

Deebo Samuel's recent declaration, "It's now or never," has ignited discussions about the San Francisco 49ers' Super Bowl ...

Star wide receiver Deebo Samuel explained why the 2024 NFL season is "now or never" time for the San Francisco 49ers' Super ...

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Coming off a wild NFL Week 2 in which eight underdogs won outright, we turn our attention to a crucial Week 3 for all the 0-2 ...

Brandon Aiyuk was asked to assess himself today in the 49ers locker room. Here's what he said. Q: How do you feel about your route running and ho ...

SANTA CLARA, Calif. (AP) — San Francisco 49ers safety Talanoa Hufanga was a full participant in practice for the first time since tearing a ligament in his knee last November and could be set to ...

Given that the calf strain to 49ers running back Christian McCaffrey suddenly and unexpectedly became an Achilles tendon, too ...

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

The San Francisco 49ers won’t have wide receiver Deebo Samuel for a couple weeks because of a calf injury he sustained late ...

The San Francisco 49ers are preparing for their Week 3 contest against the Los Angeles Rams on Sunday at SoFi Stadium in ...