With injuries sidelining their star athletes, can the 49ers rally together to secure a crucial win against the desperate Rams ...

San Francisco 49ers head coach Kyle Shanahan reveals different preparations against the Los Angeles Rams without Aaron Donald ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

Deebo Samuel's recent declaration, "It's now or never," has ignited discussions about the San Francisco 49ers' Super Bowl ...

Star wide receiver Deebo Samuel explained why the 2024 NFL season is "now or never" time for the San Francisco 49ers' Super ...

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Brandon Aiyuk was asked to assess himself today in the 49ers locker room. Here's what he said. Q: How do you feel about your route running and ho ...

DL Nick Bosa, WR Brandon Aiyuk and LB Fred Warner shared the team's mindset heading into the 2024 season, discussed the ...

Jennings may not be a household name, but he has been a rock solid No. 3 receiver for the 49ers the last couple of seasons.

SANTA CLARA, Calif. (AP) — San Francisco 49ers safety Talanoa Hufanga was a full participant in practice for the first time since tearing a ligament in his knee last November and could be set to ...

Given that the calf strain to 49ers running back Christian McCaffrey suddenly and unexpectedly became an Achilles tendon, too ...

The San Francisco 49ers had a good start to their week of practice leading up to a Week 3 showdown with the Los Angeles Rams.