SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

The 49ers woes in Minnesota continued last week when their former quarterback Sam Darnold torched his old squad. The offense ...

There are plenty of questions swirling around with the San Francisco 49ers right now with Christian McCaffrey on the Injured ...

San Francisco had its toughest practice of the week Thursday and McCaffrey was dealing with pain afterward, Shanahan said.

McCaffrey won NFL Offensive Player of the Year in 2023 and helped the 49ers reach Super Bowl 58. He’s produced 2,205 rushing ...

The San Francisco 49ers have placed All-Pro running back Christian McCaffrey on injured reserve because of his lingering calf ...

The San Francisco 49ers are without running back Christian McCaffrey for at least four weeks. A report from NFL Media’s Ian ...

ESPN sources: 49ers officially are placing All-Pro RB Christian McCaffrey on injured reserve due to his calf tightness and ...

The San Francisco 49ers have ruled out Christian McCaffrey for Week 2 vs. the Minnesota Vikings — and potentially longer.

Christian McCaffrey is breaking down the decision to sit out of the San Francisco 49ers' opening game against the New York ...

Whether it's by watching game tape or combing through statistics, Christian McCaffrey's value to the San Francisco 49ers is ...

Brandon Aiyuk’s lackluster opening to the season cannot continue with Deebo Samuel and Christian McCaffrey sidelined.