SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

49ers coach Kyle Shanahan said the timeline for running back Christian McCaffrey’s return is unknown.

The 49ers still don't know Christian McCaffrey's status for Sunday's game against the Vikings. The running back was a ...

Head coach Kyle Shanahan discussed running San Francisco's offense without RB Christian McCaffrey and WR Deebo Samuel Sr., ...

San Francisco 49ers head coach Kyle Shanahan gets real about wide receiver Deebo Samuel and running back Christian ...

San Francisco 49ers head coach Kyle Shanahan recently confirmed that both wide receiver Deebo Samuel and running back ...

San Francisco coach Kyle Shanahan said All-Pro running back Christian McCaffrey could have played in the 49ers’ opener if it ...

Kyle Shanahan said on Tuesday that part of the reason running back Christian McCaffrey sat out Monday night's game against ...

San Francisco 49ers running back Christian McCaffrey missed the team's Week 1 matchup against the New York Jets, as he's ...

49ers head coach Kyle Shanahan said running back Christian McCaffrey is dealing with both a calf injury and Achilles ...

San Francisco coach Kyle Shanahan said All-Pro running back Christian McCaffrey could have played in the 49ers’ opener if it ...

In a newsworthy weekend for the football world, San Francisco 49ers running back Christian McCaffrey being ruled out right ...