NFL San Francisco 49ers

Predictions, picks and odds for NFL Week 13 game

San Francisco has been up and down all season ... Check out expert picks and best bets for every NFL game this week. Buffalo had its bye and the 49ers are so banged up that it’s tough to back them in this spot — especially cause the Bills are hitting ...

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Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

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With only a few weeks left on the college football slate, NFL draft season is beginning to hit its stride. Before the San ...

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The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's ...

The San Francisco 49ers are 5-6 entering their matchup with the Buffalo Bills on Sunday, and an NFL executive called out ...

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What to expect from Sunday Night Football's 49ers vs. Bills matchup. This is one of those games that feels like Buffalo's to ...

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the ...

There are three NFL games happening on Thanksgiving. Here are the matchups: The Chicago Bears will face off against the ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

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