To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...

In short, these results revealed that both CRLF2 OE and CRLF2-d are correlated with poor prognosis in ALL patients.

Sickness-induced sleep is a behavior conserved across species that promotes recovery from illness, yet the underlying mechanisms are poorly understood. Here, we show that interleukin-6-like cytokine ...

Johnson & Johnson (NYSE: JNJ) has announced the FDA‘s approval of TREMFYA® (guselkumab) for adults with moderately to ...

This research topic focuses on the intricate interplay between the host immune response and potential therapeutic targets. Viral infections can exacerbate allergic conditions by dysregulating the ...

Adaptimmune received FDA approval for Tecelra, with a 39% response rate in synovial sarcoma. See why I rate ADAP stock as a ...

Inflammation and genetic mutations can drive cardiovascular complications in patients with myeloproliferative neoplasms, which include disorders such as polycythemia vera, essential thrombocythemia, ...

Glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide and dual GLP-1 and glucose-dependent insulinotropic polypeptide receptor agonists such as tirzepatide could curb both the health ...

Figure 3. Phases of the cytokine-dependent JAK/STAT signaling cascade. 1: binding of cytokines to their corresponding surface receptors induces receptor dimerization, bringing two associated JAKs into ...

Grant share is based on the ratio of number of grants to total number of patents. The patent US12043655B2 describes a novel constitutively active chimeric cytokine receptor (CACCR) designed to enhance ...

Pro-inflammatory cytokines (TNF-α ... The specific T cell receptor is responsible for recognizing antigen fragments in the form of peptides bound to major histocompatibility complex molecules.