P2X7 is a purinergic receptor that plays a crucial role in the body's response to tissue damage, inflammation, and infection ...

Elevated IL-10 in diabetes causes capillary obstruction, linked to cognitive deficits. Blocking IL-10 receptors shows promise for improving brain function.

Both novel bifunctional (SON-1411) and monofunctional (SON-1400) fusion proteins exhibit wild-type binding to the IL-18 receptor (IL-18Rc), ...

In the quest to enhance the efficacy of chimeric antigen receptor T (CAR-T) cell therapy against hepatocellular carcinoma (HCC), a recent study has identified a pivotal role for CD39 expression in ...

Cytokine and chemokine production was measured ... Cite this: Functional Interleukin-17 Receptor A is Expressed in Central Nervous System Glia and Upregulated in Experimental Autoimmune ...

A similar result was detected in a previous work where blocking of the IL-4/IL-13R type II receptor led to an inhibition of Th2 cytokine-induced H4R upregulation (21). Figure 7. Regulation and ...

Exploration of adenosine mechanism revealed adenosine receptors as a potentially useful target of therapy in RA.

Recent studies have shown that pharmacologic weight loss with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and combination therapies is approaching magnitudes achieved with surgery. However, ...