Since 2010, according to VSiN, teams that start out the season 0-2 straight up are 26-25 in Week 3, but they are 35-15-1 against the spread when playing 1-1 teams in the third week. Think about that.

We should find out whether a few of the surprising 2–0 teams are pretenders or contenders this season, including the Vikings and Steelers.

SportsLine's Projection Model reveals its top Week 3 NFL picks, NFL best bets, NFL parlay picks, NFL parlay card, NFL predictions, and 25-1 football parlay

NFL Week 3 picks, predictions, win probabilities for Patriots-Jets, Dolphins-Seahawks, Ravens-Cowboys, 49ers-Rams, Chiefs-Falcons and more games.

Fubo is offering big savings on streaming the NFL this season. You can even watch the best games of Week 3 for free.

Newsweek's sports betting analysts tackle every Week 3 game, including the Monday Night Football doubleheader of Jaguars-Bills and Commanders-Bengals.

Week 3 in the NFL will undoubtedly feature some major twists between the start of Sunday and the end of the "Monday Night Football" doubleheader.

It was a solid Week 2 for me -- at least against the spread. You would think I'd be better picking the games straight up, but that wasn't the case last week. I went 7-9 straight up for a 17-15 overall record and I was 9-6-1 ATS for a 17-12-3 record.

Last week was a great one to bet on the underdogs in the NFL. Kudos to anyone who bet on the Raiders to beat the Ravens outright at +350 (the spread was Raiders +9). For the week, the underdogs went 11-4-1 against the spread (ATS).