A total of 210 patients were randomized to a five-day course of oral or i.v. prednisolone 60 mg daily with a placebo medication ... if they had used systemic corticosteroids before study enrollment.
It is written: both systemic and topical corticosteroids can exacerbate or precipitate acne or even induce an acneform eruption. Corticosteroids are considered to be acnegenic comedogenic drugs ...