Interleukin 2, or IL-2, is a pleiotropic cytokine that plays a vital role in the regulation of T-cell responses. IL-2 also plays a crucial role in an extensive range of other immune modulatory ...

Despite setbacks for projects trying to harness the power of the cytokine interleukin-2 (IL-2) as a cancer therapy, there are still plenty of players on the field – and Roche has just joined ...

Alireza Faridar, M.D., a neurologist at Houston Methodist Hospital, looked at (PDF) the IL-2 component of the combination in an investigator-initiated trial. The study randomized 38 people with mild ...

PT101 is an engineered IL-2 mutein fused to a protein backbone ... that are trying to flip that on its head and try to use the cytokine to protect organs from autoimmune reactions.

Werewolf Therapeutics (HOWL) shared clinical and preclinical data at the 2024 Society for Immunotherapy of Cancer’s 39th Annual Meeting, ...

Elevated IL-10 in diabetes causes capillary obstruction, linked to cognitive deficits. Blocking IL-10 receptors shows promise for improving brain function.

The companies’ monoclonal antibody met co-primary endpoints in a Phase III trial in patients with chronic rhinosinusitis with ...

Researchers from Rice University and Baylor College of Medicine have demonstrated a groundbreaking treatment that eradicates advanced-stage mesothelioma tumors in mice within just a few days.

Efforts must be undertaken to develop experimental models allowing to investigate how cytokines in the tumor microenvironment impact on tumors formed by primary NB cells. Combination of IL-2 with ...

Less frequent IV dosing with nemvaleukin in patients with select advanced solid tumors, including ovarian cancer and mucosal melanoma, showed ...