Jannik Sinner vs. Daniil Medvedev prediction: US Open odds, pick, best bets Wednesday
World No. 1 Jannik Sinner, in search of his second career Grand Slam title and first US Open, is a -300 favorite against 2021 champion Daniil Medvedev. Both players were imperious in their victories in the Round of 16 and have lost just one set en route to the quarterfinals. In other words, Wednesday’s match should be a box-office hit.