Tumor-infiltrating lymphocytes and other T cell-mediated treatments, such as CAR-T, have the potential to improve the effectiveness and personalization of cancer care. Cytokines play a crucial ...

Researchers have developed a new method of locally delivering cytokines alongside T cells that could lead to improved CAR-T cell therapies. CAR-T cell therapies utilize engineered T cells that have a ...

Macrophages interact with T cells in order to bring about T cell activation in target organs, and are themselves activated by inflammatory messenger molecules (cytokines) produced by the T cells.

The CAR-T cell therapy Aucatzyl was approved for relapsed or refractory B-cell precursor acute lymphoblastic leukemia based ...

Liver failure encompasses a range of severe clinical syndromes resulting from the deterioration of liver function, triggered ...

Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by acute deterioration of liver function ...

Cytokine analysis in cancer patients reveals biomarkers for predicting immune-related adverse reactions, aiding in the ...

Like other CAR T-cell therapies, the drug's labeling has a boxed warning over risks of cytokine release syndrome (CRS), ...

While there isn't a definitive answer ... that stimulate cell pathways and allow for communication between cells. These cytokines, according to the American Cancer Society, essentially signal ...