In short, these results revealed that both CRLF2 OE and CRLF2-d are correlated with poor prognosis in ALL patients.

Recent data suggest that calcium-dependent signalling downstream of ITAM-coupled receptors regulates the amplitude and functional outcomes of cytokine and TLR signalling. In this Opinion article ...

GlobalData’s report assesses the drugs in the Interleukin 10 Receptor pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.

The CCL17/CCL22-CCR4 axis can be used as a novel biomarker for the prognosis of B-cell acute lymphoblastic leukemia (ALL), according to a new study published in the journal Cytokine. It is already ...

Sickness-induced sleep is a behavior conserved across species that promotes recovery from illness, yet the underlying mechanisms are poorly understood. Here, we show that interleukin-6-like cytokine ...

Several reports now demonstrate a role for the ligand–receptor interaction of TL1A ... a new member to the growing list of inflammatory cytokines active in the inflamed synovia of patients ...

Legend Biotech's valuation is conservative, suggesting potential for significant appreciation and growth ahead. Click here to ...

Bile acids are byproducts of cholesterol metabolism in the liver and constitute the primary components of bile. Disruption of ...

Exploration of adenosine mechanism revealed adenosine receptors as a potentially useful target of therapy in RA.

Adaptimmune received FDA approval for Tecelra, with a 39% response rate in synovial sarcoma. See why I rate ADAP stock as a ...

B-cells, crucial components of the adaptive immune system, play a multifaceted role in immune defense through antibody production, cytokine release, and antigen presentation to T-cells. By producing ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...