Brookline is a town in Norfolk County, Massachusetts, United States, and part of the Boston metropolitan area. An exclave of Norfolk County, B…Brookline is a town in Norfolk County, Massachusetts, United States, and part of the Boston metropolitan area. An exclave of Norfolk County, Brookline borders six of Boston's neighborhoods: Brighton, Allston, Fenway–Kenmore, Mission Hill, Jamaica Plain, and West Roxbury. The city of Newton borders Brookline to the west. It is known for being the birthplace of John F. Kennedy.